OSTEOMYELITIS IN PATIENTS WITH COMPLICATED FORM OF DIABETIC FOOT SYNDROME
Abstract
Diabetes mellitus, today is a worldwide problem. The number of patients is steadily growing from year to year and according to WHO, for the last 30 years, has increased more than 5 times, and at the moment is more than 500000 million people, in the Republic of Uzbekistan, about 300000 thousand people, that is about every 11 adults in the world suffer from this disease. According to the number of complications, diabetes mellitus is one of the main causes of death (AsfandiyarovaN.S., 2015, Dedov I.I., 2018, Chuan L.L., 2013, Pan X., 2020). The most significant complication, at present, is diabetic foot syndrome, which affects about 8-10% of all patients with diabetes mellitus and is the main cause of all lower limb amputations at various levels. One of the complications of SDS, is osteomyelitis of the bones of the foot, developing against the background of infection of soft tissues and bones of the foot, with diabetic neuropathy and osteoarthropathy, according to one study complicates the course of the disease in 15% of patients (Hinchliffe.,2016, Walsh.,2017., Marphy- Lovoie.,2021), according to other data up to 50-60% ( Lazaro Martinez.,2019., Antsyferov M.B., 2007, Dedov I.I., Jeffcoate W., 2004) and leads to limb amputations. "International Working Group on the diabetic foot, 2015", considers the "gold standard" in the diagnosis of osteomyelitis in SDS, clinical, radiographic picture, bacteriology and histology of bone tissue. Detected microflora growth and histologic findings of bone infection are important for the diagnosis.
References
Antsiferov M.B., Galstyan G.R., Tokmakova A.Y., Dedov I.I. Diabetic foot syndrome. Diabetes Mellitus, 2001, 2: 2-8. /Antsiferov MB, GalstyanGR, Tokmakova AYu, Dedov II. Diabetic foot syndrome. Sakharny Diabet, 2001,
Artykova D.M., Shagazatova B.H., Urunbaeva D.A. et al. Diabetic foot syndrome. Bulletin of the Council of Young Scientists and Specialists of Chelyabinsk.Bulletin of the Council of Young Scientists and Specialists of the Chelyabinsk Region. 2015; 2 (9): 70-76.
Clinical guidelines for the diagnosis and treatment of diabetic foot syndrome. Wounds and wound infections, 2015, 2 (3): 63-83./ Clinical guidelines for the diagnosis and treatment of diabetic foot syndrome. Rany i Ranevye Infektsii, 2015, 2 (3): 63-83.
Apelqvist J, Bakker K, van Houtum WH, Schaper NC, International Working Group on the Diabetic Foot (IWGDF) Editorial Board . Practical guidelines on the management and prevention of the diabetic foot: based upon
Dedov I.I. Diabetes mellitus: development of technologies in diagnosis, treatment and prevention.2010; 3: 1-13
Dedov I.I., Shestakova M.V., Vikulova O.K. State Register of Diabetes Mellitus. State Register of Diabetes Mellitus in the Russian Federation: 2014 status and prospects. Federation: 2014 status and prospects of development. Diabetes Mellitus. 2015; 18 (3): 5-22.
Dedov I.I., Shestakova M.V., Galstyan G.R. et al. Algorithms of specialized medical assistance to patients with diabetes mellitus. Algorithms of specialized medical care for patients with diabetes mellitus; Edited by I.I. Dedov, M.V. Shestakova. Dedov, M.V. Shestakova (7th issue). Diabetes mellitus. Abet. 2015; 18 (1S): 1-112.
Balabolkin MI, Klebanova EM, Kreminskaya VM. Pathogenesis of angiopathies in diabetes mellitus. 1999; 1: 1-8
